Biodesign is a whole new category in tissue repair that combines the best attributes of synthetic mesh and biologic grafts. It is not prone to erosion or stretching, and it leaves behind strong, fully vascularized tissue that functions and moves naturally.

Biodesign’s 4 key benefits make it an advanced material when compared to synthetic mesh and other biologic grafts.

• Signals the body
• Resistant to infection
• Complete remodeling
• Long-term strength

Learn more About Biodesign.
Learn more about Cook Biotech and access more technical information about Biodesign.

Dermis-based biologic grafts are more resistant to infection than synthetic mesh and allow some natural remodeling. However, they contain elastin that is left behind in the body to stretch, sometimes resulting in a recurrence of the original tissue failure. Some biologic grafts are chemically cross-linked in an attempt to compensate for this stretching. This can create a biologic graft that will not fully remodel. Most biologic grafts are also limited in availability and size, and can be cost-prohibitive.

Biodesign, on the other hand, is not chemically cross-linked and does not leave behind a significant amount of elastin. It signals the body to encourage complete remodeling, so it becomes strong, organized tissue that is resistant to infection. Widely available for a moderate price in specially designed shapes and sizes, Biodesign encompasses the best attributes of both biologic grafts and synthetic mesh (see question below), creating a whole new category in tissue repair.

Learn more about How Biodesign Is Different.

While synthetic mesh is readily available in various shapes and sizes and is fairly inexpensive, it can lead to scarring and encapsulation, is contraindicated in infected fields, and has potential for erosion into surrounding tissue. In some cases synthetic mesh needs to be removed after implant, requiring a second surgery.

Biodesign, however, signals the body to restore itself, so the patient’s own defense and repair mechanisms act to heal the area rather than attack or encapsulate the graft as a foreign substance. Thus, it is resistant to infection, encourages complete remodeling, and is not prone to erosion or encapsulation. It leaves behind strong, fully vascularized tissue that functions and moves naturally. Biodesign offers a permanent repair without a permanent material.

Biodesign encompasses the best attributes of both biologic grafts (see question above) and synthetic mesh, creating a whole new category in tissue repair.

Learn more about How Biodesign Is Different.

Since the development of Biodesign, this new category of tissue repair material has been studied and written about extensively in medical journals. To date, more than 700 articles have been published about the material from which Biodesign (originally called Surgisis or SIS) is created.

Learn more about Evidence for Biodesign.

If you have additional questions, please contact your Cook Medical representative.

Any surgery has potential for complications. The following complications are possible with the use of Biodesign surgical mesh: bleeding, infection, abscess, induration, acute or chronic inflammation (initial application of surgical graft materials may be associated with transient, mild, localized inflammation), allergic reaction, visceral adhesions, fistula formation, seroma formation, hematoma, extrusion, recurrence of tissue defect, and delayed or failed incorporation of the device. See Instructions for Use for specific complications related to a particular product.