Biodesign is designed to reduce recurrence by giving the body a way to remodel strong, vascularized patient tissue, without long-term complications.
Long-term strength: A meta-analysis
The graph above shows recurrence over time for Biodesign, acellular human dermis, and cross-linked porcine dermis in both clean and complex fields according to a 2009 meta-analysis by Hiles, et al. Updated through June 2011.1, 2
A best fit line has been added representing recurrence data from a recent study of porcine dermis-based biologic grafts in contaminated fields by Itani, et al.
1 Hiles M, Record Ritchie RD, Altizer AM. Are biologic grafts effective for hernia repair?: a systematic review of the literature. Surg Innov. 2009;16(1):26-37.
2 Data on file at Cook Biotech.
3 Awad S, Baumann D, Bellows C, et al. Prospective multicenter clinical study of single-stage repair of infected or contaminated abdominal incisional hernias using Strattice™ Reconstructive Tissue Matrix. Poster presented at: American College of Surgeons Clinical Congress; October 3-7, 2010; Washington DC.