Biodesign is designed to reduce recurrence by giving the body a way to remodel strong, vascularized patient tissue, without long-term complications.

Long-term strength: A meta-analysis

The graph above shows recurrence over time for Biodesign, acellular human dermis, and cross-linked porcine dermis in both clean and complex fields according to a 2009 meta-analysis by Hiles, et al. Updated through June 2011.1, 2

A best fit line has been added representing recurrence data from a recent study of porcine dermis-based biologic grafts in contaminated fields by Itani, et al.

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1 Hiles M, Record Ritchie RD, Altizer AM. Are biologic grafts effective for hernia repair?: a systematic review of the literature. Surg Innov. 2009;16(1):26-37.

2 Data on file at Cook Biotech.

3 Awad S, Baumann D, Bellows C, et al. Prospective multicenter clinical study of single-stage repair of infected or contaminated abdominal incisional hernias using Strattice™ Reconstructive Tissue Matrix. Poster presented at: American College of Surgeons Clinical Congress; October 3-7, 2010; Washington DC.


NOTE: Any surgery has the potential for complications. The following complications are possible with the use of Biodesign® Advanced Tissue Repair Products: bleeding, infection, abscess, induration, acute or chronic inflammation (initial application of surgical graft materials may be associated with transient, mild, localized inflammation), allergic reaction, visceral adhesions, fistula formation, seroma formation, hematoma, extrusion, recurrence of tissue defect, and delayed or failed incorporation of the device. Not all part numbers listed on this website are approved for sale in all regulatory jurisdictions. Consult with your local Cook representative or customer service center for details.